Publications & Posters
- Publication
- Pharmaceutics
Safety of Repeated Administration of Xenogeneic Human Apoptotic State (Allocetra-OTS) in Sprague Dawley Rats
Chen Ankri, et al
- Publication
- Frontiers in Immunology
Apoptotic cells for treatment of acute respiratory distress syndrome associated with COVID-19
Peter Vernon van Heerden, Avraham Abutbul, Ahmad Naama, Shlomo Maayan, Nassar Makram, Akiva Nachshon, Kamal abu Jabal, Oren Hershkovitz, Lior Binder, Yehudit Shabat, Barak Reicher, and Dror Mevorach, Frontiers in Immunology.
- Poster
- ASCO 2023. Boston, IL USA
Enlivex therapeutics macrophage reprogramming as a paradigm shift in the treatment of life-threatening indications with unmet medical need
Hershkovitz, et al
- Poster
- ISCT 2023. Paris, France
Development of a frozen formulation of Allocetra-OTS, an innovative macrophage reprogramming cell-based therapy
Amor-Baroukh, et al
- Poster
- ISCT 2023. Paris, France
In-vitro biological activity characterization and cell-based potency assay development for Allocetra-OTS,a novel macrophage reprogramming cell therapy developed for the treatment of sepsis
Ankri, et al
- Poster
- ASCO 2022. Boston, MA USA
Allocetra-OTS, an Early Apoptotic Cellular Therapy Synergize with Immune Check Point Inhibitors and Chimeric Antigen Receptor (CAR) T Cell Therapy Against Peritoneal Solid Tumor
Mevorach, et al
- Poster
- ISCT 2022. San Francisco, CA USA
Allocetra-OTS, an Early Apoptotic Cellular Therapy Synergize with Chimeric Antigen Receptor (CAR) T Cell Therapy or Immune Check Point Inhibitor Against Peritoneal Solid Tumor
Mevorach, et al
- Poster
- ISCT 2022. San Francisco, CA USA
Treatment with Allocetra–OTS in 21 severely/critically ill patients with COVID-19, leading to swift discharge and cytokine storm resolution
Van Heerdan, et al
- Publication
- Frontiers in Immunology
Apoptotic Cells for Therapeutic Use in Cytokine Storm Associated With Sepsis– A Phase Ib Clinical Trial
Peter Vernon van Heerden, Avraham Abutbul, Sigal Sviri, Eitan Zlotnick, Ahmad Nama, Sebastian Zimro, Raja el-Amore, Yehudit Shabat, Barak Reicher, Batla Falah and Dror Mevorach
- Publication
- Cell Death & Disease
Apoptotic cell therapy for cytokine storm associated with acute severe sepsis
Netanel Karbian, Avraham Abutbul, Raja el-Amore, Ran Eliaz, Ronen Beeri, Barak Reicher and Dror Mevorach
- Publication
- Joint IIS-ISCR Special Conference
Synergism between human apoptotic cell infusion (Allocetra-OTS) and human chimeric antigen receptor (CAR)- T therapy in fighting solid human tumor in SCID Bg mice
Dror Mevorach
- Publication
- Frontiers in Immunology
The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer
Nadège Bercovici, Marion V. Guérin, Alain Trautmann and Emmanuel Donnadieu
- Publication
- Frontiers in Immunology
Apoptotic Cells induced Signaling for immune Homeostasis in Macrophages and Dendritic Cells
Uriel Trahtemberg and Dror Mevorach
- Publication
- PLOS ONE
Identification and Characterization of Two Human Monocyte-Derived Dendritic Cell Subpopulations with Different Functions in Dying Cell Clearance and Different Patterns of Cell Death
Trahtemberg U, Grau A, Tabib A, Atallah M, Krispin A, Mevorach D.
- Publication
- PLOS ONE
Apoptotic Cells Induce NF-κB and Inflammasome Negative Signaling
Amir Grau, Adi Tabib, Inna Grau, Inna Reiner, Dror Mevorach
- Publication
- Nature reviews
Apoptotic cell clearance: basic biology and therapeutic potential
Ivan K. H. Poon, Christopher D. Lucas, Adriano G. Rossi and Kodi S. Ravichandran
- Publication
- Biology of Blood and Marrow Transplantation
Single Infusion of Donor Mononuclear Early Apoptotic Cells as Prophylaxis for Graft-versus-Host Disease in Myeloablative HLA-Matched Allogeneic Bone Marrow Transplantation: A Phase I/IIa Clinical Trial
Dror Mevorach
- Publication
- Annals of the New York Academy of Sciences
What do we mean when we write “senescence,” “apoptosis,” “necrosis,” or “clearance of dying cells”?
Mevorach D, Trahtemberg U, Krispin A, Attalah M, Zazoun J, Tabib A, Grau A, Verbovetski-Reiner I.
- Publication
- The New York Academy of Sciences
Role of class A human thrombospondins in the clearance of dying cells and tolerance induction
Tabib A, Krispin A, Mevorach D.
- Publication
- Apoptosis
Clearance of dying cells and systemic lupus erythematosus: the role of C1q and the complement system
Mevorach D.
- Publication
- European Journal of Immunology
iC3b-opsonized apoptotic cells mediate a distinct anti-inflammatory response and transcriptional NF-kB-dependent blockade
Gil Amarilyo, Dror Mevorach, et al
- Publication
- Human Immunology
Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages
Tassiulas I, Park-Min KH, Hu Y, Kellerman L, Mevorach D, Ivashkiv LB.
- Publication
- Blood
Apoptotic cell thrombospondin-1 and heparin-binding domain lead to dendritic-cell phagocytic and tolerizing states
Krispin A, Bledi Y, Atallah M, Trahtemberg U, Verbovetski I, Nahari E, Zelig O, Linial M, Mevorach D.
- Publication
- The Journal of Experimental Medicine
Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7
Verbovetski I, Bychkov H, Trahtemberg U, Shapira I, Hareuveni M, Ben-Tal O, Kutikov I, Gill O, Mevorach D.