Publications & Posters

2024

• Publication
• Pharmaceutics 2024, vol. 16(3), 426

Safety of Repeated Administration of Xenogeneic Human Apoptotic State (Allocetra-OTS) in Sprague Dawley Rats

Chen Ankri, et al

2023

• Publication
• Frontiers in Immunology 2023, vol. 14:2

Apoptotic cells for treatment of acute respiratory distress syndrome associated with COVID-19

Peter Vernon van Heerden, et al.

2023

• Poster
• ASCO 2023. Boston, IL USA

Enlivex therapeutics macrophage reprogramming as a paradigm shift in the treatment of life-threatening indications with unmet medical need

Hershkovitz, et al

2023

• Poster
• ISCT 2023. Paris, France

Development of a frozen formulation of Allocetra-OTS, an innovative macrophage reprogramming cell-based therapy

Amor-Baroukh, et al

2023

• Poster
• ISCT 2023. Paris, France

In-vitro biological activity characterization and cell-based potency assay development for Allocetra-OTS,a novel macrophage reprogramming cell therapy developed for the treatment of sepsis

Ankri, et al

2022

• Poster
• ASCO 2022. Boston, MA USA

Allocetra-OTS, an Early Apoptotic Cellular Therapy Synergize with Immune Check Point Inhibitors and Chimeric Antigen Receptor (CAR) T Cell Therapy Against Peritoneal Solid Tumor

Mevorach, et al

2022

• Poster
• ISCT 2022. San Francisco, CA USA

Allocetra-OTS, an Early Apoptotic Cellular Therapy Synergize with Chimeric Antigen Receptor (CAR) T Cell Therapy or Immune Check Point Inhibitor Against Peritoneal Solid Tumor

Mevorach, et al

2022

• Poster
• ISCT 2022. San Francisco, CA USA

Treatment with Allocetra–OTS in 21 severely/critically ill patients with COVID-19, leading to swift discharge and cytokine storm resolution

Van Heerdan, et al

2021

• Publication
• Frontiers in Immunology 2021, vol. 12

Apoptotic Cells for Therapeutic Use in Cytokine Storm Associated With Sepsis– A Phase Ib Clinical Trial

Peter Vernon, et al

2020

• Publication
• Cell Death & Disease 2020, vol. 11, art. 535

Apoptotic cell therapy for cytokine storm associated with acute severe sepsis

Netanel Karbian, et al

2019

• Poster
• Joint IIS-ISCR Special Conference

Synergism between human apoptotic cell infusion (Allocetra-OTS) and human chimeric antigen receptor (CAR)- T therapy in fighting solid human tumor in SCID Bg mice

Dror Mevorach

2019

• Publication
• Frontiers in Immunology 2019, vol. 10: 1563

The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer

Nadège Bercovici, et al

2017

• Publication
• Frontiers in Immunology 2017, vol. 8: 1356

Apoptotic Cells induced Signaling for immune Homeostasis in Macrophages and Dendritic Cells

Uriel Trahtemberg, et al

2016

• Publication
• PLoS One 2016, vol. 11(9): e0162984

Identification and Characterization of Two Human Monocyte-Derived Dendritic Cell Subpopulations with Different Functions in Dying Cell Clearance and Different Patterns of Cell Death

Uriel Trahtemberg et al.

2015

• Publication
• PLoS One 2015, vol. 10(3): e0122440

Apoptotic Cells Induce NF-κB and Inflammasome Negative Signaling

Amir Grau et al.

2014

• Publication
• Nature Reviews | Immunology 2014, vol. 14, p.166–180

Apoptotic cell clearance: basic biology and therapeutic potential

Ivan K. H. Poon, et al

2014

• Publication
• Biology of Blood and Marrow Transplantation 2014, vol. 20(1), p.58-65

Single Infusion of Donor Mononuclear Early Apoptotic Cells as Prophylaxis for Graft-versus-Host Disease in Myeloablative HLA-Matched Allogeneic Bone Marrow Transplantation: A Phase I/IIa Clinical Trial

Dror Mevorach

2010

• Publication
• Annals of the New York Academy of Sciences 2010, 1209:1-9

What do we mean when we write “senescence,” “apoptosis,” “necrosis,” or “clearance of dying cells”?

Dror Mevorach, et al

2010

• Publication
• Annals of the New York Academy of Sciences 2010, 1209:43-8

Role of class A human thrombospondins in the clearance of dying cells and tolerance induction

Adi Tabib, et al

2010

• Publication
• Apoptosis 2010, vol. 15(9): 1114-23

Clearance of dying cells and systemic lupus erythematosus: the role of C1q and the complement system

Dror Mevorach

2010

• Publication
• European Journal of Immunology 2010, vol. 40(3), p.699-709

iC3b-opsonized apoptotic cells mediate a distinct anti-inflammatory response and transcriptional NF-kB-dependent blockade

Gil Amarilyo, et al

2007

• Publication
• Human Immunology 2007, vol. 68(3): 156-64

Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages

Ioannis Tassiulas, et al

2006

• Publication
• Blood 2006, vol. 108(10): 3580-9

Apoptotic cell thrombospondin-1 and heparin-binding domain lead to dendritic-cell phagocytic and tolerizing states

Alon Krispin, et al

2002

• Publication
• The Journal of Experimental Medicine 2002, vol. 196(12): 1553-61

Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7

Inna Verbovetski, et al